Incisional SSI were observed in 4 patients (4.7%) in the study group and in 27 patients (10.7%) in the control group ( p = 0.097). Median time to NPWT removal was 4 (IQR 3–5) days. In total, 85 patients (25%) in the study group were comparable with 252 (75%) patients in the control group regarding demographics (age, gender, body mass index, ASA score), ostomy type and anastomotic technique (all p > 0.05), but not wound contamination class (class III: 5% vs 0%, p < 0.001). Data was retrieved from the institutional enhanced recovery after surgery (ERAS) database, with standardized complication assessment by trained abstractors. SSI was defined in accordance with the Center of Disease Control (CDC) classification and included superficial and deep incisional SSI. Primary outcome was iSSI rate within 30 days of surgery. Since November 2018, all patients (study group) received a NPWT device for a maximum of 5 days postoperatively (PICO, SMITH AND NEPHEW). Intradermal non-purse string technique with absorbable sutures were used in all patients. Single-center retrospective analysis of consecutive patients undergoing ileo- or colostomy closure over an 8-year period (January 2013-January 2021). The aim of this study was to compare iSSI rates in patients after ostomy closure with and without additional application of a closed-wound NPWT dressing. Closed-wound negative pressure wound therapy (NPWT) dressings were recently introduced with the purpose to reduce incisional surgical site infections (iSSI) in high-risk wounds.
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